Action of 3-methylquercetin on poliovirus RNA replication.
نویسندگان
چکیده
3-Methylquercetin is a natural flavone that powerfully blocks poliovirus replication. This compound inhibits selectively poliovirus RNA synthesis both in infected cells and in cell-free systems. Poliovirus double-stranded RNA (replicative forms) is still made in the presence of this inhibitor, whereas the synthesis of single-stranded RNA and the formation of replicative intermediates are drastically blocked.
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عنوان ژورنال:
- Journal of virology
دوره 61 10 شماره
صفحات -
تاریخ انتشار 1987